It’s unlikely as ICANN has said that it will retire the domain if io is removed from ISO 3166-1 https://www.icann.org/en/blogs/details/the-chagos-archipelago-and-the-io-domain-14-11-2024-en

No it would be the first. .su is still considered a CCTLD http://www.iana.org/domains/root/db/su.html

That would make it the only 2 letter non country code top level domain. And could also cause issues if another country is later assigned io as it’s 2 letter country code by ISO

https://www.reddit.com/r/slaythespire/comments/t3habp/the_first_proof_of_an_unwinnable_slay_the_spire/

There is technically an unwinnable sts seed